Match-making for posaconazole through systems thinking
نویسندگان
چکیده
منابع مشابه
Match-making for posaconazole through systems thinking.
Currently available drugs for Chagas' disease are limited by toxicity and low efficacy in the chronic stage. Posaconazole, the most advanced new anti-chagasic drug candidate, did not fully confirm its initial potential in a Phase II clinical trial for chronic Chagas' disease. Given that posaconazole is highly active against Trypanosoma cruzi in vitro, and was very well tolerated in clinical tri...
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ژورنال
عنوان ژورنال: Trends in Parasitology
سال: 2015
ISSN: 1471-4922
DOI: 10.1016/j.pt.2014.11.004